Soluble CD30 Levels in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Patients
نویسندگان
چکیده
منابع مشابه
Hodgkin lymphoma transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma.
Transformation to a large cell lymphoma may occur during the course of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) in approximately 5% of the cases. This is known as Richter's transformation. A much less frequent transformation to Hodgkin lymphoma may occur. We report a case of CLL/SLL in which a transformation to Hodgkin lymphoma occurred, and we review previously publish...
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ABSTR ACT: The survival of patients with chronic lymphocytic leukemia (CLL) has significantly improved in the last 30 years. The introduction of purine analogs in the treatment armamentarium followed by the combination of these compounds with alkylating agents first improved response rates and progression-free survival (PFS) when compared with alkylating agent-based therapy only. However, the g...
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Sporadic Burkitt lymphoma (BL) accounts for 1% to 2% of lymphomas in adults. The abdomen is the most common site of involvement. The 2008 World Health Organization Classification of Tumors of Haematopoietic and Lymphoid Tissues introduced a new category of high-grade B-cell lymphomas: an entity with overlapping features of both diffuse large B-cell lymphoma and Burkitt lymphoma (DLBCL/BL). Thes...
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A 39-year-old man noted a pigmented lesion on his back that had been growing for ;1 year. A punch biopsy demonstrated malignant melanoma, nodular type. He was also found to have a white blood cell count of 45.8 3 10/mL and palpable axillary, cervical, and inguinal lymph nodes. The blood was sent for flow cytometry and demonstrated a population of small CD19 B cells that were l light chain restr...
متن کاملClinical Significance of Plasma Levels of Soluble CD40 in Patients with Chronic Lymphocytic Leukemia
CD40 ligation provides signals central to chronic lymphocytic leukemia (CLL) cell survival and proliferation. The release of soluble CD40 (sCD40) may impact on both these signals and CD40 targeted therapies. In this study we investigated the prognostic significance of plasma sCD40 in untreated CLL patients (n = 34). We report that 56% had levels higher than those of normal donors and that eleva...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2014
ISSN: 1943-7722,0002-9173
DOI: 10.1093/ajcp/142.suppl1.088